U.S. Route 64

Explore U.S. Route 64, a scenic and historic highway stretching from North Carolina’s Outer Banks to New Mexico’s high desert. Discover key cities, attractions, and travel highlights along this iconic east-west route.

U.S. Route 64 is a major east–west highway spanning approximately 2,300 miles across the southern and central United States. It begins in the scenic Outer Banks of North Carolina at Whalebone Junction and stretches westward all the way to the Arizona border in northeast New Mexico, just east of the town of Teec Nos Pos. Along its path, US 64 passes through a diverse array of landscapes, including coastal plains, the Appalachian Mountains, fertile farmland, and desert mesas.

The highway serves as a vital connector through six states: North Carolina, Tennessee, Arkansas, Oklahoma, New Mexico, and a brief portion of eastern Arizona. In the eastern states, US 64 closely parallels major interstates like I-40 but often provides a more scenic or locally accessible alternative. In the west, especially through Oklahoma and New Mexico, it cuts through rural areas and tribal lands, including a picturesque stretch through the Cimarron Canyon and the Sangre de Cristo Mountains.

U.S. Route 64 intersects with numerous important routes, including I-75 in Tennessee, I-35 in Oklahoma, and US 285 in New Mexico. Its role as a regional thoroughfare is enhanced by its proximity to natural and cultural attractions such as the Great Smoky Mountains, Memphis, the Ozarks, and Taos. This blend of utility and charm makes US 64 a favorite for both long-haul drivers and road-tripping travelers seeking a less-traveled path across the heart of America.

Discover U.S. Routes

U.S. Route 64: Pulaski to Fayetteville – Tennessee

U.S. Route 64: Pulaski to Fayetteville – Tennessee

Explore U.S. Route 64 from Pulaski to Fayetteville, Tennessee — a 20-mile drive through Giles and Lincoln Counties that blends farmland, rolling hills, and a modern bypass around Fayetteville’s historic core.

Join us for a 32-mile drive across northeastern Oklahoma as we follow U.S. Route 64 from Sand Springs to Bixby, weaving through urban expressways, interchanges, and small-town charm along the way.

U.S. Route 64: Sand Springs to Bixby – Oklahoma

Join us for a 32-mile drive across northeastern Oklahoma as we follow U.S. Route 64 from Sand Springs to Bixby, weaving through urban expressways, interchanges, and small-town charm along the way.

Drive 33 miles along U.S. Highway 64 from Beebe to Conway, Arkansas, through scenic farmland, small towns like El Paso and Vilonia, and into the growing urban hub of Conway. Experience this diverse slice of central Arkansas in our latest road video.

[Revisited] U.S. Route 64: Beebe to Conway – Arkansas

Drive 33 miles along U.S. Highway 64 from Beebe to Conway, Arkansas, through scenic farmland, small towns like El Paso and Vilonia, and into the growing urban hub of Conway. Experience this diverse slice of central Arkansas in our latest road video.

U.S. Route 64: Conway to Beebe – Arkansas

U.S. Route 64: Conway to Beebe – Arkansas

Travel 37 miles along U.S. Route 64 from Conway to Beebe, Arkansas. This drive highlights downtown Conway, a bypass around Vilonia, and scenic rural farmland in White County before ending at I-57 in Beebe.

U.S. Route 64: Conway to Russellville – Arkansas

U.S. Route 64: Conway to Russellville – Arkansas

Cruise west from Conway to Russellville along U.S. Route 64, a 46-mile drive through small towns, farmlands, and scenic stretches of Arkansas River Valley. A charming alternative to I-40 packed with local flavor.

U.S. Route 74: Cleveland – Tennessee

U.S. Route 74: Cleveland – Tennessee

Cruise along the U.S. 64 Bypass in Cleveland, Tennessee, as we follow U.S. Route 74 for 7 miles around the city’s southern edge—connecting local routes to Interstate 75 and helping traffic avoid the downtown core.

U.S. Highway 64: Memphis to Bolivar – Tennessee

U.S. Highway 64: Memphis to Bolivar – Tennessee

Cruise east for 45 miles on U.S. Highway 64 from Memphis to Bolivar, Tennessee. This drive blends suburban sprawl, small-town stops, and open farmland — a relaxing snapshot of southwest Tennessee.

U.S. Highway 64: Van Buren to Alma – Arkansas

U.S. Highway 64: Van Buren to Alma – Arkansas

Cruise from historic Van Buren to Alma along U.S. Highway 64 in western Arkansas. This short, scenic route passes through farmland and small-town streets, offering a charming look at the Arkansas River Valley away from the busy interstates.