Interstate 65

Explore Interstate 65, a major north-south route from Mobile, AL to Gary, IN, connecting key cities like Birmingham, Nashville, and Indianapolis along its nearly 900-mile journey.

Interstate 65 (I-65) is a major north-south corridor in the central United States, stretching from Mobile, Alabama, to Gary, Indiana. As one of the key arteries of the Interstate Highway System, it serves as a vital link between the Gulf Coast and the Great Lakes region. I-65 passes through four states—Alabama, Tennessee, Kentucky, and Indiana—and connects major cities including Birmingham, Nashville, Louisville, and Indianapolis.

The route is heavily used for both commercial and personal travel, supporting industries from agriculture and manufacturing to logistics. Its alignment closely follows historic north-south travel corridors and is often used as a primary freight route. I-65 intersects with several major east-west interstates, including I-10, I-20, I-40, I-70, and I-80/94, making it a key part of the national transportation grid.

Along its 887-mile stretch, drivers encounter a mix of urban skylines, rolling hills, and rural farmland. Notable features include the scenic Tennessee River crossing, the massive interchange with I-70 in Indianapolis known as the “North Split,” and the towering Mobile River Bridge at its southern end. I-65 continues to play a pivotal role in the movement of people and goods across the central United States.

Drive the Interstates

Drive 3.4 miles north on Interstate 65 through Birmingham, Alabama, from the I-20/59 interchange to the junction with I-22. This industrial corridor passes through rail yards, historic neighborhoods, and vital freight routes, linking central Birmingham with the expanding I-22 corridor.

Interstate 65: Birmingham – Alabama

Drive 3.4 miles north on Interstate 65 through Birmingham, Alabama, from the I-20/59 interchange to the junction with I-22. This industrial corridor passes through rail yards, historic neighborhoods, and vital freight routes, linking central Birmingham with the expandin…

Explore a short but vital stretch of Interstate 65 southbound through Birmingham, Alabama, from the I-22 interchange to the dramatic downtown convergence with I-20/I-59. Discover the skyline views, surrounding neighborhoods, and key infrastructure along this urban connector.

[Revisited] Interstate 65: Southbound in Birmingham – Alabama

Explore a short but vital stretch of Interstate 65 southbound through Birmingham, Alabama, from the I-22 interchange to the dramatic downtown convergence with I-20/I-59. Discover the skyline views, surrounding neighborhoods, and key infrastructure along this urban conne…

Southbound Interstate 65 in Birmingham, Alabama

Southbound Interstate 65 in Birmingham, Alabama

Cruise southbound on Interstate 65 through Birmingham, Alabama, for 3 bustling miles of urban driving — from Daniel Payne Drive near I-22 all the way to the interchange with Interstates 20 and 59 in the city center.

Interstate 65: Louisville to Elizabethtown – Kentucky

Interstate 65: Louisville to Elizabethtown – Kentucky

Travel 45 miles along Interstate 65 from downtown Louisville to Elizabethtown, Kentucky, passing city skylines, airport interchanges, Fort Knox access points, and rolling rural hills on this vital central Kentucky route.

Interstate 70 / 65 / 465: A Loop Through Indianapolis

Interstate 70 / 65 / 465: A Loop Through Indianapolis

Take a scenic urban drive through Indianapolis along I-70, I-65, and I-465, exploring the heart of the Hoosier State’s highway system. From the east side beltway to downtown and back west, follow a route that showcases the city’s energy, history, and infrastructure …

Interstate 65: Southbound in Indianapolis – Indiana

Interstate 65: Southbound in Indianapolis – Indiana

Drive 4 miles south on Interstate 65 through downtown Indianapolis, Indiana. Explore how this vital urban corridor connects city neighborhoods and has changed since the major North Split reconstruction was completed in 2023.

Interstate 65: Nashville to Mitchellville – Tennessee

Interstate 65: Nashville to Mitchellville – Tennessee

Drive Interstate 65 from downtown Nashville to the Kentucky state line at Mitchellville, Tennessee. Explore 37 miles of scenic highway, suburban landscapes, and pastoral countryside on this northbound route through Middle Tennessee.