Take a smooth ride across the rolling eastern Tennessee foothills as we follow Interstate 40 from Midway to the crossroads at Dandridge, where I-81 branches northeast toward the Appalachians. This 19-mile stretch blends wooded ridgelines, open farmland, and the steady pull of regional traffic flowing between Knoxville and the Tri-Cities. Despite being a major interstate, this is one of those stretches where nearby overlooks and trails add to the trip, offering a glimpse of rural Tennessee just beyond the guardrails.
We begin near mile marker 402, in the unincorporated community of Midway, a place defined more by pastoral landscapes than by town limits. As we merge onto eastbound I-40, the interstate eases into a gentle series of curves, threading between wooded hillsides and pockets of farmland. Development thins quickly compared to Knoxville just minutes behind us, and the route takes on a relaxed, transitional feel. The Midway Road interchange sits just to the west, providing local access to Mascot, Trentville, and the communities along US-25W, where travelers often find unexpected stops in these communities just off the highway.
East of Midway, the interstate begins to settle into the long glide toward Douglas Lake, though the water remains hidden behind the tree line for much of this drive. The landscape opens slightly between Kodak and Beech Springs, where farms, small churches, and low ridgelines define the view in both directions. Traffic tends to be steady but manageable here, with tractor-trailers and regional commuters sharing the broad, well-maintained roadway. Passing under Tennessee Route 66, we travel just north of the gateway corridors leading toward Sevierville and the Great Smoky Mountains—one of those moments where you’re reminded that if you’re curious about what’s around you, this route has a lot to offer only a short drive to the south.
Approaching mile marker 417, the corridor grows slightly busier as we near Dandridge, one of Tennessee’s oldest towns and the county seat of Jefferson County. Though the interstate does not enter the historic core, its proximity is clear in the increasing number of local access roads and the subtle rise in development around the exits. Wooded hills give way to broader clearings, and the wide interchange geometry ahead hints at the major junction that defines this segment of I-40.
The drive concludes at Exit 421, where Interstate 40 meets Interstate 81, the primary northeast corridor toward Morristown, Bristol, and southwest Virginia. The junction unfolds across a sweeping, elevated interchange—a familiar sight for anyone traveling between the Deep South and Appalachia. Continuing straight keeps you on I-40 toward Newport and the mountains beyond, while the left lanes split toward I-81, carrying travelers into Tennessee’s northeastern valleys and eventually toward the Mid-Atlantic states. As we roll through the interchange, the route again balances the sense of long-distance travel with the quiet presence of rural Tennessee, a fitting transition at one of the state’s most important crossroads.
🗺️ Route Map


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